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Mechanistically, BPC-157 is proposed to work through several overlapping pathways in these animal studies: modulation of the nitric-oxide system, upregulation of growth-factor and growth-hormone receptors in target cells, promotion of angiogenesis via VEGFR2 signaling, and a stabilizing effect on the gut-brain axis and vascular integrity

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NRF2 is then able to translocate into the nucleus and activate the expression of genes critical for protecting the cell

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