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These reactions are the -ketoacyl-ACP reductase and enoyl-CoA reductase catalyzed steps indicated as reaction 5 and 7 in the Figure below (details in the Synthesis of Fatty Acids page)
466 Additionally, DCQD attenuates kidney inflammation by modulating inflammatory cytokines, 467 improves intestinal function via the regulation of barrier proteins, 468 and reduces serum levels of HMGB1, thereby alleviating AP-ALI, 469 reflecting its systemic protective profile
To clarify if these alterations represent only a consequence or causatively contribute to intestinal inflammation, more research is needed
Marcel Dekker
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