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In addition, gamma-glutamyl transferase (GGT) levels exhibit a negative association with cognitive performance, while elevated alkaline phosphatase (ALP) levels increase the risk of A deposition, PET burden, and cognitive impairment [60]

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The following framework reflects common clinical approaches

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Last Published 05.01.2026 Effective Date: 05.01.2026 This policy addresses the use of Veopoz (pozelimab-bbfg) for the treatment of CD55-deficient protein-losing enteropathy (PLE) (i.e., CHAPLE disease)

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