10.1523/ENEURO.0263-18.2019 eNeuro Summary Keywords neurodegenerative diseases, ferroptosis, nuclear factor E2 related factor 2 (Nrf2/NFE2L2), glutathione peroxidase 4 (GPX4), regulation mechanism Citation Song X and Long D (2020) Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases
As estrogen levels decline during perimenopause and menopause, the brain becomes less efficient at using glucose, its primary fuel source
Metformin
I will admit that this isnt very common, but if you have a patient who is having substantial weight loss that is necessitating new medications like mirtazapine or megestrol, youve got to reassess the risk/benefit of continuing the GLP-1
Therefore, erythrophagocytosis-induced ferroptosis contributes to the formation of larger atherosclerotic plaques, but this effect can be reversed by UAMC-3203 (Puylaert et al., 2023)
Reduction in the Incidence of Type 2 Diabetes With Lifestyle Intervention or Metformin