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The resulting lysates were directly subjected to qPCR using primers specific to the mouse mitochondrial genome

10.1016/S2213-8587(20)30074-7 [DOI] [PubMed] [Google Scholar] 33.Ji L, Agesen RM, Bain SC et al (2024) Efficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: PIONEER 12, a double-blind, Phase IIIa, randomised trial

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But usually, we have a decent idea of whats working and whats not. The mechanistic logic for gut effects has a known route