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This is consistent with the fact that NAC, like most thiols, is a poor scavenger of hydrogen peroxide and superoxide (Winterbourn and Metodiewa, 1999)

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Concentrations are reported in pmol/mL

Back in 2010, the US Food and Drug Authority (FDA) concluded that increases in the incidence of carcinomas among rodents translated into a low risk for humans, because statistically significant increases occurred only at drug-exposure levels many times those anticipated in humans

Unfortunately, little in vitro data is available for the effects of capmatinib on head and neck cell lines