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Hypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer

Supplementation: Glutathione 500 mg daily, polypodium extract 480 mg twice daily

For insect feeding and pathogen inoculation assays, plants were grown in soil for 45 weeks at 22 C with a 10 h/14 h light/dark (short day, SD) photoperiod