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This narrative review aims to bridge the gap between evidence and clinical practice regarding the use of GLP-1 RAs in the perioperative period by critically evaluating changing clinical recommendations to inform a balance between the risks of aspiration and the potential surgical benefits

41 As discussed above, mitochondrial dysfunction (mitochondrial bioenergetics, calcium buffering) and mitochondrial quality control systems (mitochondrial dynamics, mitophagy, mitochondrial biogenesis) may be involved in the pathological mechanisms of diabetes-related NDs

doi:10.1001/jama.2023.2438 6

When taken this way, GLP-1 becomes a tool not just for weight loss but for long-term vitality

Not surprisingly, patients who took the drugs for more months and those who took semaglutide lost more weight

By mimicking the effects of the hormone GLP-1, this tailored treatment has significant potential in managing appetite and enhancing feelings of fullness