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This activation leads to the release of cortisol and other stress hormones, which can initiate or exacerbate migraine episodes (Stubberud et al., 2021)

OCTN1, organic cation/carnitine transporter 1

Thus, it is imperative that more in vivo studies focusing specifically on atherosclerosis are done to better understand how monocyte and macrophage biology is altered in the setting of G6PD-d

The neurotoxicity of IFN- is well established (298), as well as the cognitive impairment induced by this cytokine (299)

Furthermore, therapeutic evidences in pre-clinical models of inflammatory skin disease have been also reported 31,32,33