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Each year the participants underwent a battery of neuropsychological tests to evaluate their cognitive function

Drug modification and combination therapy related to butyrate Modifying butyrate Continuous intravenous infusion of sodium or arginine butyrate caused a sudden increase in blood concentration, resulting in various acute toxicities, especially hypokalemia [94, 95]

Circu and Aw, 2012

The mechanism is attributed to the drug class

Lamarre SG, Molloy AM, Reinke SN, Sykes BD, Brosnan ME, Brosnan JT

In vitro and in vivo experiments demonstrated that drug-loaded micelles significantly enhanced the efficacy of RSL3 in inducing ferroptosis in drug-resistant cancer cells, thereby weakening the multidrug resistance (MDR) of anticancer drugs