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Somatostatin has multiple effects on anterior pituitary as well as pancreatic, liver and gastrointestinal function: It inhibits GH secretion indirectly via antagonizing GHRH secretion

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Mast Cell Hyper-Reactivity (MCAS): As a potent antioxidant, glutathione neutralizes the reactive oxygen species that directly trigger mast cell degranulation, helping to stabilize these immune cells and reduce the systemic release of inflammatory mediators

71 Across these levels, enhanced neuronal synchrony, increased burst firing, and shifts in frequency tuning toward audiometric edge frequencies have been identified as consistent correlates of tinnitus

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