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Description

Hepatic effects reported in 0.1% to 1% of patients during clinical trials of topiramate as monotherapy or adjunct therapy for epilepsy included elevated hepatic enzymes (ALT, AST)

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The benefits of SGLT2i therapy also extends to CKD where there is a significantly reduced risk of decline in eGFR and progression to end stage renal failure, regardless of presence or absence of type 2 diabetes [23]

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