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Researchers investigating neuroendocrine pulse architecture have therefore favoured ipamorelin over longer-acting non-peptide analogues when preserving physiological pulsatility is a study design requirement

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Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

Matuz-Mares et al., 2021)

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FDA concerns on file include peptide impurities, inadequate characterization, and immunogenicity risk from inconsistent synthesis