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DOI: 10.1111/j.1365-2133.2006.07376.x [ Links ] 18

As expected, the ROS level was significantly increased (~1520%) by GSTM2 knockdown ( p 90% similarity

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In MDD, this peripheral-central coupling is likely amplified by BBB dysfunction characterized by increased permeability, neurovascular inflammation, and associations with symptom severity [172, 173] thereby lowering the threshold at which peripheral KP activation translates into central glutamatergic, oxidative, and neuroimmune dysregulation

Auch im Rahmen von Erkrankungen kommt es hufig zu einem Glutathion-Mangel