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The preferential loss of visceral fat with GLP-1 therapies produces disproportionate improvements in inflammatory status compared to weight lost from other body regions

Its important to inject semaglutide GLP-1 on the same day each week, and it can be administered with or without food

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The side effect profiles differ somewhat , with tirzepatide showing similar GI effects but potentially different patterns of onset and resolution

Semaglutide has been structurally modified to prevent it from being broken down by an enzyme in the blood called dipeptidyl peptidase-4 or DPP-4