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We anticipate that Pfizer will find a new footing

Among women with PCOS, semaglutide or tirzepatide prescribing increased from 2.4% in 2021 to 17.6% in 2025, a more than 7-fold increase

Those have the potential to provide metabolic effects without increasing side effects of pruritus and elevated LDL

However, because the Wegovy pill contains the same active ingredient as the Wegovy injection (semaglutide), the same modest heart-rate increase noted across the GLP-1 class may apply, so cardiovascular assessment before starting and monitoring during treatment remain appropriate

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doi: 10.1182/blood-2007-08-108050 60 FrauwirthKARileyJLHarrisMHParryRVRathmellJCPlasDRet al