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In addition, they observed that DNA demethylases ROS1 , DME , and DML2 were downregulated in damaged fruits after CS

The protection appears to result from the peptide's ability to bypass inhibitory IGFBP interactions, allowing more effective activation of IGF-1 signaling pathways that enhance sarcolemmal stability and reduce membrane damage during eccentric contractions

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Urinary GSH levels also tended to decrease after sulfasalazine treatment, possibly due to the reduction of TLS (Figures 4 and 6C)

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