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Summary Clinical studies highlight that GLP-1RA to treat obesity, alongside their concomitant cardioprotective effects, have become a hallmark in clinical science

Neuroimaging studies have consistently demonstrated reduced D2R availability, reflected by decreased binding potential, in key striatal and extrastriatal regions of obese individuals, supporting an association between obesity, central dopaminergic hypofunction, and dysregulated prolactin homeostasis ( 5 Mechanisms by which obesity may promote hyperprolactinemia We have systematically analyzed the potential mechanisms by which hyperprolactinemia promotes obesity

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A meta-analysis of 27 randomised controlled trials found that berberine significantly reduced fasting blood glucose, HbA1c, triglycerides, total cholesterol, and LDL cholesterol

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3 Sublingual troche format designed for simple, consistent use without injections