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Side effects may include skin irritation or allergic reactions
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The study did not demonstrate conventional immediate pharmacological sedation, and the authors proposed that DSIP might influence sleep regulation rather than act like a standard hypnotic medicine
Additionally, the observation that changes in symptoms as assessed by PainDetect are correlated with changes in the CNFD in the ARA 290 treatment group alone, further support a functional relationship between small fiber density and neuropathic symptoms
