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What We Still Dont Know While the scientific theory and early studies on ipamorelin may be promising, there are no long-term clinical trials to support the claims that it regulates metabolism, fuels weight loss, builds muscle, aids sleep, or generally controls any other variety of aging-related ailments

But how does it stack up against semaglutide and tirzepatide

doi: 10.1210/jc.2004-1788 92

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It helps inhibit the enzyme tyrosinase, which can shift the skin toward producing lighter pigments and reducing the appearance of dark spots and hyperpigmentation