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Treatments with DSIP and the DSIP-CBBBP fusion peptide significantly countered this reduction, showcasing their potential as therapeutic agents for modulating hedonistic behavior

This finding was mechanistically supported by an enhanced antifungal effect of fluconazole in a VVC vaginal epithelial cell model and mouse model when administered together with vitamin B complex injection 81

These treatments include vaginal lubricants and moisturizers, vaginal estrogen, HRT, and non-estrogen prescription options

Those with MTHFR gene mutations lack the enzyme required to activate folic acid, which can result in a buildup of unmetabolized folic acid (UMFA)

We therefore turned to a detailed computational model of 1-carbon metabolism to revisit the remethylation-block hypothesis and investigate the lack of correlation between vitamin B 12 deficiency and GSH

Neuropeptides 45 , 205211 (2011)