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Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G et al

Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis

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(2) by secreting lactate

Beyond single pathway inhibition: MEK inhibitors as a platform for the development of pharmacological combinations with synergistic anti-leukemic effects

Whether this stable form demonstrates equivalent biological activity to the standard research compound in human subjects is itself a question that warrants dedicated study