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Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn's disease

Directed evolution of LaccID: generation 3 For the third round of evolution, three libraries were generated using G2 (LacAnc100 + Q45R;R121S) as the starting template

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Cost: Costs can vary, but in general IV NAD+ is the most expensive option (each infusion can cost anywhere from $250 to $1,000+ depending on dose/clinic)

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Cao F, He YS, Wang Y, Zha CK, Lu JM, Tao LM, et al