Knight MG, Anekwe C, Washington K, Akam EY, Wang E, Stanford FC
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doi: 10.1186/1742-2094-10-142 119 AragoCNSouzaLLCabanelasAOliveiraKJPazos-MouraCC
Among 69,221 propensity-matched patients with IBD, those who had received a GLP-1 RA had a 5-year colorectal cancer incidence of 0.2% compared with 0.42% in non-GLP-1 RA users (OR, 0.49), corresponding to a 51% reduction in odds of developing colorectal cancer
One substance that has in recent years appeared in news reports is acetyl-L-carnitine
It is currently believed that CP is actively metabolized in the kidney cells to produce a potent nephrotoxic metabolite (Miller et al., 2010)