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Therapeutic phlebotomy is the controlled removal of a measured amount of blood to reduce red blood cell concentration and restore healthy blood viscosity

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Thirdly, activated mTOR enhances wound healing in DFU by upregulating the expression of multiple growth factors, 83 regulating the accumulation of lipids in endothelial cells and fibroblasts, 84 inducing epithelial-mesenchymal transition, 85 and promoting the proliferation and differentiation of fibroblasts