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Efficacy and safety of early-start deferiprone in infants and young children with transfusion-dependent beta thalassemia: evidence for iron shuttling to transferrin in a randomized, double-blind, placebo-controlled, clinical trial (START)

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However, the latest study provides a novel idea for the mechanism of TMAO promoting thrombosis, i.e., an increase in TMAO results in promotion of tissue factor (TF) expression in the vascular endothelium