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This work was supported by grants from the Chung Shan Medical University Hospital (CSH-2022-A-004)

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This system would enable in silico pre-screening of natural products, with top candidate compounds subsequently validated in human organoidzebrafish chimera models

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Additionally, many NRF2-regulated metabolic pathways were found to confer growth advantages to cancer cells, such as the upregulation of the PPP, nucleotide synthesis, and NADPH production

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