Various cationic polymers, including polyethylenimine (PEI), polyamidoamine dendrimers (PAMAM), poly-L-lysine (PLL), poly--aminoester (PBAE), and poly-lactic-co-glycolic acid (PLGA), have been developed for this purpose (Fig
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This effect was evidenced by improved uptake of soluble antigens, elevated expression of genes encoding IL-6, TNF-, iNOS, and IL-1, and a marked increase in nitric oxide production (223, 224)
Extra B12 is usually removed from the body within 48 hours, depending on urine volume
Toxic effects of drugs used in the ICU
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