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206 Specifically, iron-induced oxidative stress causes increased release of iron from iron-containing proteins, converting Fe 3+ to Fe 2+ intracellularly

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Moreover, eryptosis has been demonstrated to be induced by NPs [459] or high-molecular-weight polysaccharides [494] without their uptake but with accumulation around the cells, suggesting that eryptosis might be induced by shear stress via piezo1 mechanosensitive Ca 2+ ion channels

10.1016/j.jinorgbio.2019.110749 24 ChainoglouE.Hadjipavlou-LitinaD

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Healthy-volunteer studies reported changes in attention, operator performance, EEG measures, or functional connectivity after intranasal exposure [1] [2]