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Wei F-C, Mardini S

Wiley Online Library This mechanism addresses a fundamental limitation of GLP-1R-only and GLP-1R/GIPR approaches: those compounds reduce energy intake primarily, but have limited ability to increase resting energy expenditure

This recommendation supersedes the CDEC recommendation for this drug and indication dated October 4, 2022

Mounjaro represents the next generation, adding a second hormone receptor to the mechanism

Intermittent Treatment Strategies Many patients and providers now discuss whether GLP-1 therapy should continue long-term or cycle intermittently based on individual metabolic stability, weight regain rate, and treatment tolerance

These FDA approved weight loss medications can help you lose weight faster than diet or exercise alone