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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets

Circ Res 127(4):486501 Wang Y, Yan S, Liu X, Deng F, Wang P, Yang L, Hu L, Huang K, He J (2022) PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway

Genet 139 , 911918, (2020)

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However, they're also the ones to be the most affected by oxygen free radicals, peroxide that damage them and the integrity of the cells themselves

Interestingly, adding exogenous ROS induced by TBHP led to PDCs with high expression of VRK2 susceptibility to APR-017 treatment (Fig