FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data
If you're on BP medication, keep an eye on your readings Nausea with oral use: Uncommon, but some people get mild stomach upset when taking it orally
Excipient Interaction and Incompatibility Studies in Injectable Pharmaceutical Formulations
If you want results, use injectable
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Both compounds are once weekly