Reference Canfora et al., Nature Reviews Endocrinology (2019) 2
Pancreatitis: GLP-1s can contribute to pancreatitis, or inflammation of the pancreas that can lead to complications if left untreated
After one week of CARNITOR therapy (3 doses), all patients had trough concentrations between 54 and 180 mol/L (normal 40-50 mol/L) and concentrations remained relatively stable or increased over the course of the study
What GLP-1s Do Much of the excitement around GLP-1s comes from their ability to address two critical challenges: weight and blood sugar control
Reduced expression of glutathione s-transferase alpha 4 promotes vascular neointimal hyperplasia in ckd
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