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C-tracing experiments in butyrate-treated Caco-2 cells demonstrated rapid C incorporation into histone acetylation marks within 30 min, directly confirming its role as an acetylation substrate provider [56]

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The liver sections of the paracetamol-treated rats showed an altered lobular shape and a nuclear disintegration in certain locations as well as disarrangement of normal hepatic cells, necrosis, and fatty degeneration