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Observations that DPP4 levels and activity were elevated in T cells of patients with autoimmune disorders and inflammatory conditions including rheumatoid arthritis (134) led to evaluation of DPP4 inhibitors for treatment of immune disorders involving aberrant T-cell function

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The gut microbiota-related antihyperglycemic effect of metformin

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The T cells were then cocultured with NY-ESO-1 and A375 tumor cells in a 3:1 ratio for 24 h before labeling with BMP for 2 h (Fig