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Patients with peripheral neuropathy often see meaningful improvement with consistent therapy

To avoid aggravation of anxiety, it is important to start with the lowest possible dose of an antidepressant and then work up slowly, over two or three weeks

10.2174/13816128130105 27 DjakovicZ.DjakovicI.CesarecV.MadzaracG.BecejacT.ZukanovicG.et al (2016)

Some of these factors include the cellular composition and vascular nature of the tissue(s) in question