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New target-based therapies that block pro-inflammatory cytokine receptors, lymphocytic infiltration or the insulin-like growth factor 1 receptor (IGF1R) have been tested in several clinical trials and show promising results in Graves orbitopathy

What might slow progress is the anxiety loop that follows a suspected bad injection

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Novo Nordisk already has a drug with the same active ingredient (which is called semaglutide) in pill form, although it is currently approved only for diabetes (sold under the brand name Rybelsus)

& Oppenheim, J

doi:10.1007/s00726-007-0537-9