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There are various therapeutic targets including cytokine, intracellular signaling pathways i.e., JAKs, keratinocyte proliferation and differentiation and vascular changes

It serves as a direct precursor to nitric oxide which is a molecule that helps blood vessels relax, thereby improving circulation

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Unless otherwise prescribed by your doctor, the usual dose is: At the start of treatment, 1 ml (1 ampoule) is administered once or twice a week for the first two weeks after diagnosis, corresponding to 1000-2000 g of cyanocobalamin per week

Murakami S, Takayama S, Ikezawa K, Shimabukuro Y, Kitamura M, Nozaki T, et al