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2.3 Experimental protocol Following 1 week of acclimation, six rats were allocated randomly to one of four groups: Rats in Group 1, the control group, were given saline intraperitoneally (IP) twice weekly for 6 weeks
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When elevated host oxygenation disrupts the intestinal radial oxygen gradient, it alters the microbial composition, promoting the enrichment of oxygen-tolerant bacteria while significantly suppressing strict anaerobes, such as Anaerostipes, which produce SCFAs (117)
A 2021 study in obese adults undergoing severe caloric restriction found that liposomal glutathione 1000mg daily preserved lean muscle mass better than placebo, though the mechanism was attributed to reduced inflammatory signaling rather than direct anabolic effects
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