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[DOI] [PubMed] [Google Scholar] 28.Hiraoka A, Kiguchi D, Ninomiya T, et al

MW: Writing original draft, Writing review & editing

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However, it has limited CNS bioavailability and lacks specificity, contributing to short-lived efficacy and side effects including confusion and hallucinations 60,61

This article covers the exact pharmacokinetic timeline, the metabolic and biological factors that accelerate or delay onset, and what realistic expectations look like across different administration protocols