Tirzepatide is FDA-approved for type 2 diabetes (as Mounjaro) and for obesity (as Zepbound)
Y., Stothard, P
2.6 Meta-analysis Meta-analysis was performed using the R statistical program, R version 4.4.2 (The R Foundation for Statistical Computing, Wirtschaftsuniversitt Wien, Vienna, Austria) (Viechtbauer, 2010), employing a random-effect model via the metafor R package ( 3 Results 3.1 Study selection and characteristics The search strategy identified 2,183 potential articles: 1,299 from PubMed, 353 from Scopus, 527 from Embase, 4 from manual screening
"Vitamin B12 deficiency A 21st century perspective"
Have a look on mumsnet for old posts
General Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord