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Although the incidence of adverse events (AEs) between bimagrumab and placebo was similar, there was a transient increase in pancreatic and liver enzyme levels observed with the use of bimagrumab [97]

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This enhanced efficacy was attributed to the improved dispersibility and higher reactivity of highly oxidized GO, which promotes oxidative stress, membrane disruption, and bacterial trapping

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Nausea, diarrhea, and vomiting were the most common complaints, occurring primarily during dose escalation periods

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GSTs are phase 2 enzymes, ubiquitously distributed in the cell

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