2 Methods 2.1 Eligibility criteria This meta-analysis was registered prospectively in PROSPERO (CRD420251147337) and was carried out following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) recommendations
Kelly DL, Sullivan KM, McEvoy JP, McMahon RP, Wehring HJ, Gold JM, et al
Dark-side of exosomes
[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Tournebize J., Sapin-Minet A., Bartosz G., Leroy P., Boudier A
Identify the population
Symptoms tend to be worse at night and can include numbness, difficulty feeling pain or temperature changes, tingling or burning sensation, sharp pains, or cramps, increased sensitivity, or hypersensitivity to touch, muscle weakness, loss of reflexes, loss of balance and coordination, serious foot problems (ulcers, infections, deformities, bone and joint pain) - When affecting multiple nerves/nerve groups (polyneuropathy) or a single nerve/ nerve group mononeuropathy Common Medications: - Lyrica (pregabalin) - Neurontin (gabapentin) - Carbamazepine (off-label) -Duloxetine (off-label) Work Cited: Optum HCC Coder