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They found that when people stop these medications after an average of 39 weeks of treatment, they generally regain weight rapidly, and their cardiometabolic markers return to pre-GLP-1 levels by 1.4 years after treatment has been discontinued

Extra fat cells act like mini chemical factories, releasing hormones and inflammatory messengers called cytokines, such as interleukin-6 (IL-6), Tumor necrosis factor alpha (TNF-alpha), interleukin-17 (IL-17), and others