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However, it remains unclear which cells or organs are responsible for the beneficial metabolic effect of Grn depletion

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The pathogenesis of AIH is characterized by T lymphocyte activation, release of pro-inflammatory cytokines, infiltration, and destruction of hepatic parenchyma, resulting in sustained immune-mediated liver injury and functional impairment [246]

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The two processes are collectively referred to as direct photolysis or indirect photolysis, and both mechanisms contribute to the removal of pollutants

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