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Another patient with stomach sensitivity may not tolerate the same medication schedule
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JAMA Intern Med 2016;176:1474-81.ArticlePubMed 38
While the mechanistic insights are encouraging, further clinical investigations are needed to isolate the direct analgesic effects of GLP-1R agonists from those mediated by weight loss
Depending on the individual medicine and its FDA-approved indication, GLP-1 receptor agonists may: Stimulate insulin release when blood glucose is elevated Reduce glucagon secretion Slow stomach emptying Increase feelings of fullness Support lower blood glucose Help some patients reduce body weight Semaglutide is a GLP-1 receptor agonist available in several prescription products
AE were similar between bimagrumab and placebo, although bimagrumab was associated with transiently elevated pancreatic and liver enzymes [97]
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