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Food and Drug Administration (FDA) does not approve dietary supplements for safety and effectiveness before they are sold to the public

Int J Clin Nutr Diet

There is also a theoretical safety concern specific to BPC-157s biology

In patients with IBD, it is usually described a reduced bacterial diversity, with a decreased relative abundance of Firmicutes and an increase in pro-inflammatory bacteria, such as Proteobacteria, or adherent-invasive Escherichia coli or mucolytic bacteria such as Ruminococcus gnavus and Ruminococcus torques [37]