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10.1038/s41580-020-00324-8 35 JiaoY.YongC.ZhangR.QiD.WangD

Patients should inform their physician if they have: Personal history of any cancer, including colorectal cancer or polyps Family history of colorectal cancer, especially in first-degree relatives Inflammatory bowel disease (Crohn's disease or ulcerative colitis) Genetic syndromes associated with increased cancer risk (Lynch syndrome, familial adenomatous polyposis) Previous radiation therapy to the abdomen or pelvis These factors affect baseline colorectal cancer risk independent of medication use

For 10mg vial: Add 2 mL of bacteriostatic water concentration = 5 mg/mL

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As tirzepatide gradually clears from your system over 3 to 4 weeks, you may experience a transition period during which side effects evolve and your body readjusts to functioning without the medication's effects