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HbA1c Reduction observed: Orforglipron 3 mg dose: 1.3% decrease Orforglipron 12 mg dose: 1.6% decrease Orforglipron 36 mg dose: 1.5% decrease Placebo: 0.1% decrease Orforglipron compared to placebo resulted in a significant reduction in HbA1c at all tested doses