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Evaluating causal protective effect of dual GLP-1R/GIPR agonists on MASLD: a Mendelian randomization and colocalization study

doi: 10.1056/NEJMoa2502081

The prolonged half-life ensures that therapeutic drug concentrations remain stable between doses, allowing continuous engagement with GLP-1, GIP, and glucagon receptors throughout the dosing interval

If your BMI at the start of the therapy is below a certain threshold and you are not experiencing other risks or conditions, it may not be enough on its own to be eligible for the Bridge Program

Key Takeaways Retatrutide is a triple hormone receptor agonist that targets both fat loss and muscle preservation, enabling weight management for obesity

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